background: potential association of leptin (lep) gene polymorphisms has been suggested in the processes leading to breast cancer initiation and progression. we investigated whether genetic variations in the lep -2548g/a gene are associated with risk of breast cancer. methods: this case-control study consisted of 100 breast cancer cases and 100 control subjects without breast cancer that matche...

1 Center for Advanced Molecular Imaging and Translation, Chang Gung Memorial Hospital, Linkou 333, Taiwan 2Department of Nuclear Medicine, Chang Gung Memorial Hospital, No. 5, Fu-Hsin Street, Kweishan, Linkou, Taoyuan 333, Taiwan 3 INSERM, UMR1101 LaTIM, CHRU Brest, 29609 Brest, France 4Division of Diagnostic Imaging, Department of Imaging Physics, The University of Texas MD Anderson Cancer Cen...

1 Institut TELECOM, TELECOM Bretagne, UMR CNRS 3192 Lab-STICC, Technopôle Brest-Iroise CS 83818, 29238 Brest Cedex∼3, France 2Université Européenne de Bretagne, (UeB), France 3 Institut TELECOM, TELECOM Bretagne, Technopôle Brest-Iroise CS 83818, 29238 Brest Cedex∼3, France 4Laboratoire CRISTAL, Ecole Nationale de Sciences de L’Informatique (ENSI), Campus Universitaire de la Manouba, 2010 Manou...

Cristina Bagacean*,1,2,3,4, Mihnea Zdrenghea4, Christelle Le Dantec1,2, Adrian Tempescul1,2,5, Christian Berthou1,2,5 & Yves Renaudineau1,2,3 1U1227 B Llymphocytes & Autoimmunity, University of Brest, INSERM, IBSAM, Brest, France 2Labex IGO, Networks IC-CGO & REpiCGO from ‘Canceropole Grand Ouest’, Brest, France 3Laboratory of Immunology & Immunotherapy, Brest University Medical School Hospital...

The purpose of breast cancer screening is to save lives. To have confidence that the national programme can achieve this aim it must be shown firstly that mortality reductions have been conclusively demonstrated in a relevant pilot study and secondly that these benefits can be reproduced in everyday practice. The Forrest report [1] was released when the encouraging results of the Health Insuran...

1 UMR6197, Laboratoire de Microbiologie des Environnements Extrêmes, IFREMER, Technopôle Brest Iroise, Plouzané, France, 2 Laboratoire de Microbiologie des Environnements Extrêmes, UMR6197, Université de Bretagne Occidentale, Plouzané, France, 3 Centre National de la Recherche Scientifique, Laboratoire de Microbiologie des Environnements Extrêmes, UMR6197, Technopôle Brest Iroise, Plouzané, Fra...